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One of the easiest ways that companies can avoid animal exams are to use items that are already extensively found in human history and also have proven their safety over time. Companies could also depend upon data from natural and synthetic ingredients which are already previously tested on animals. Computer modeling and databases may be used to determine biological properties of ingredients and make risk assessments. Though the concept of animal testing might seem trivial, tests are less simple as smearing cold cream or lip gloss for the face of the rabbit. Animals found in laboratory testing, often proceed through extremely painful experiments and millions die every year. Those that survive the experiments don't get set free, instead they may be euthanized. In cosmetic animal testing; rabbits, guinea pigs, mice and rats can be used. Tests are done on finished products and individual ingredients to look for the products amount of toxicity and power to cause eye or skin irritations, allergies along with other harmful effects. The general manner in which people persuade the other person is dependant on many different factors: