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Jonathan Brandstein, Patrice O'Neal's manager, said family members wished to thank "all from the fans and friends that have expressed an outpouring of love and support for Patrice these past weeks." "Many people choosing a lump sum a detailed and loved friend; all people have forfeit a true comic genius' Jonathan Brandstein said in a statement. Charlie Sheen who was simply fired from your hit CBS comedy 'Two and a Half Men' in September tweeted: "The entertainment world plus the world at large lost an excellent man. Patrice O'Neal was obviously a regular guest for the program 'Opie & Anthony Radio Show' and was a familiar face at some New York City TV shows like "Chappelle Show," "The Office," and "Tough Crowd with Colin Quinn. Patrice O'Neal's death was announced on Twitter by Opie in the Opie & Anthony Radio Show on Sirius/XM satellite radio: 'Yes, it's true that our pal Patrice O'Neal has passed away,' Opie tweeted. 'The funniest and finest thinker I've ever known PERIOD. #devastated." The details of his funeral will likely be updated soon. Feelings of being fearful or powerless 2. How aggressive they're Muscle Milk contains MSG (mono-sodium glutamate), and this is really a neuro-toxin. Now glutamate is really a common neurotransmitter within our brain and is also naturally occurring. Glutamate attaches itself to neurotransmitters and excites them in order to function properly. But if your neurotransmitters get too excited then you'll get damage occurring with your brain.