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One of the easiest ways that companies can avoid animal testing is to work with products that are actually extensively utilized in human history and still have proven their safety after a while. Companies also can depend on data from natural and synthetic substances that are already previously tested on animals. Computer modeling and databases may be used to determine biological properties of ingredients making risk assessments. Speaking of mating season, that?s when you will hear essentially the most vocalization between frogs, by using a number of loud croak-like calls to draw potential mates. Each varieties of tree frog has his very own special call. Females hear select which call matches their species. The familiar ?ribbet? call, often imitated or used in the entertainment world, emanates from the Baja California tree frog.