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The main objective of the what are known as IR35 legislation is usually to prevent contractors using the tax benefits associated with operating through their very own personal company. This means people working via limited companies would be be subject to the same degrees of tax as 'normal employees', with the appropriate levels of taxes & national insurance. Feelings of being fearful or powerless Metoprolol can be an anti-hypertensive (blood pressure) drug classified like a selective beta-1 receptor blocker, also called a beta adrenergic blocker. Metoprolol is sold within the brands Lopressor and Toprol-XL and is also accessible in immediate-release and prolonged-release formulations. In addition to high blood pressure, metoprolol is prescribed to treat conditions including angina pectoris (chest pain) abnormal heart rhythms, migraine, tremors, congestive heart failure, bleeding through the esophagus, negative effects of antipsychotics, and to prevent second strokes.