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If in a very room or building, Claustrophobia sufferers may constantly be checking for doorways and exits or standing near exits even during large rooms, and feeling fear when doors are closed. Smalls spaces like cars, planes and lifts ca also bring anxious feelings. In some cases being in these situations can bring on panic disorder, in extreme cases just going to a closed door may cause a Panic Attack. Famous battle sites, man-made wonders, Mother Nature in all her splendor and World Heritage Sites are all listed in their itineraries. World renowned game parks where people can view Africa's Big 5 in their natural surroundings and natural splendors such as Vic Falls give tourists an all encompassing appreciation for this continent and its wonders. Those that support animal testing claim that is a necessary practice. They explain that businesses that rely on animal testing do use humane ways to feed, house and care for the animals. Supporters also claim that alternatives to animal testing aren't as far reaching, lacking the opportunity to figure out how cosmetic products affect living tissue and organs.