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The main reason why these companies overlook the advantages which can be obtained through absorbing natural compounds in the skin is the greater cost of using plant oils, waxes, and extracts. It requires less processing to make use of chemical based components in cosmetics, which ensures you keep cost down. Synthetic compounds are not any match for all those natural ones with regards to healing your skin. Jonathan Brandstein, Patrice O'Neal's manager, said family members planned to thank "all with the fans and friends who have expressed an outpouring of love and support for Patrice these past weeks." "Many people have mislaid an in depth and loved friend; all folks have forfeit a true comic genius' Jonathan Brandstein said inside a statement. Charlie Sheen who was simply fired in the hit CBS comedy 'Two and a Half Men' in September tweeted: "The entertainment world as well as the world most importantly lost a fantastic man. Patrice O'Neal was obviously a regular guest for the program 'Opie & Anthony Radio Show' and would have been a familiar face at some New York City TV shows including "Chappelle Show," "The Office," and "Tough Crowd with Colin Quinn. Patrice O'Neal's death was announced on Twitter by Opie in the Opie & Anthony Radio Show on Sirius/XM satellite radio: 'Yes, it's true that our pal Patrice O'Neal has passed away,' Opie tweeted. 'The funniest and finest thinker I've ever known PERIOD. #devastated." The details of his funeral will be updated soon.