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When looking at the number of ineffective anti-aging natual skin care products available on the market one has to not only consider the major cosmetics manufacturers, but on the wholesale skin care market too. It is using this market the many ?breakthroughs? come from, as new ingredients for decreasing the wrinkles in your skin are developed by companies outside of the cosmetics industry. Comedian and radio personality Patrice O'Neal died at 41 with a New York-area hospital on Tuesday morning because of a stroke he suffered back in October after having a long battle with diabetes. Patrice O'Neal is survived by his wife, Vondecarlo Brown, his stepdaughter, Aymilyon, his sister, Zinder, and the mother, Georgia. Acute stress disorder