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Counterfeit Medicines are rampant in today?s society. The most vicious victims are generally received from developing and fewer western world which can't afford expensive medicines and also have been patronizing generic brands. These brands are mostly purchased from small pharmacy counters which are generally not licensed and therefore are not allowed to use with the municipality. One of the easiest ways that companies can avoid animal testing is to work with products that are actually extensively utilized in human history and still have proven their safety after a while. Companies also can depend on data from natural and synthetic substances that are already previously tested on animals. Computer modeling and databases may be used to determine biological properties of ingredients making risk assessments.