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Jonathan Brandstein, Patrice O'Neal's manager, said your family desired to thank "all with the fans and friends who have expressed an outpouring of love and support for Patrice these past weeks." "Many individuals have lost a close and loved friend; all of us have mislaid a real comic genius' Jonathan Brandstein said in the statement. Charlie Sheen who has been fired through the hit CBS comedy 'Two and a Half Men' in September tweeted: "The entertainment world along with the world at large lost a brilliant man. Patrice O'Neal was a regular guest around the program 'Opie & Anthony Radio Show' and was a familiar face at some New York City TV shows such as "Chappelle Show," "The Office," and "Tough Crowd with Colin Quinn. Patrice O'Neal's death was announced on Twitter by Opie in the Opie & Anthony Radio Show on Sirius/XM satellite radio: 'Yes, it's true that our pal Patrice O'Neal has passed away,' Opie tweeted. 'The funniest and best thinker I've ever known PERIOD. #devastated." The details of his funeral will be updated soon. We all have days when it is an utter struggle only to get out of bed. We wish we are able to simply sleep all day long. We need to locate some kind of motivation, some reason to face your day ahead. At work we quite often find ourselves pushing aside particular tasks. Somehow we can't get ourselves to complete them so we keep finding other pursuits to function on, awaiting that elusive mood arrive at us in order to get things moving along. Even relationships sometimes are afflicted by periods when either or both sides might be experiencing individual conditions that keep these things from nurturing their link with their partner.